# China scientists shed light on male infertility (HT Tech)

> Source: https://tech.hindustantimes.com/tech/news/china-scientists-shed-light-on-male-infertility-story-i6SYfZ0Xj1pTgSV5J7Wy3M.html

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# China scientists shed light on male infertility

## Scientists in Hong Kong and China have identified a protein in sperm from humans and from mice that could be responsible for many unexplained cases of male infertility.

Updated on: May 31 2007, 17:55 IST

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Scientists in Hong Kong and China have identified for the first time a protein in sperm from humans and from mice that could be responsible for many unexplained cases of male infertility.

Defective versions of the protein, called epithelial ion channel, have previously been reported to be responsible for female infertility.

Writing in the latest issue of the Proceedings of National Academy of Sciences journal, the researchers said they detected the protein in sperm samples from mice and human subjects.

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'(The protein) is involved in the transport of bicarbonate, which is required for sperm activation in order to fertilize the egg. If you have a defect in this (protein), then fertilization capacity of the sperm will be impaired or reduced,' Chan Hsiao Chang, physiology professor at the Chinese University in Hong Kong, said in a telephone interview on Thursday.

Experiments showed that sperm taken from mutant mice with defective versions of the protein had far lower fertility than sperm taken from normal mice, the researchers said.

The discovery would help doctors more accurately diagnose and explain many cases of male infertility that have so far gone unexplained.

'For many people, they are infertile, but they don't know why, so diagnosis would be the immediate advantage,' Chan said.

Between 8 percent and 12 percent of couples with women of childbearing age -- or between 50 and 80 million people -- are infertile globally, according to the World Health Organisation.

Half of infertile couples fail to reproduce because of problems with male fertility.

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First Published Date: 31 May, 14:51 IST

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[₹20000 you should consider"> sendGA4Events(this), 0)" data-item-widget-name="gaming" data-item-story-type="story" data-item-story-title="Top 5 gaming monitors under ₹20000 you should consider" data-item-target-url="tech.hindustantimes.com/gaming/news/top-5-gaming-monitors-under-rs-20000-you-should-consider-71762254759956.html" data-item-product-position="1" data-item-story-segment="news" data-item-event="story_click" data-item-page-name="story page" data-item-widget-element="image"> ₹20,000," /> ### sendGA4Events(this), 0)" data-item-widget-name="gaming" data-item-story-type="story" data-item-story-title="Top 5 gaming monitors under ₹20000 you should consider" data-item-target-url="tech.hindustantimes.com/gaming/news/top-5-gaming-monitors-under-rs-20000-you-should-consider-71762254759956.html" data-item-product-position="1" data-item-story-segment="news" data-item-event="story_click" data-item-page-name="story page" data-item-widget-element="title"> Top 5 gaming monitors under ₹20000 you should consider](https://tech.hindustantimes.com/gaming/news/top-5-gaming-monitors-under-rs-20000-you-should-consider-71762254759956.html)
[sendGA4Events(this), 0)" data-item-widget-name="gaming" data-item-story-type="story" data-item-story-title="Grab gaming consoles at discounted rates during Amazon Great Indian Festival: Up to 72% off" data-item-target-url="tech.hindustantimes.com/gaming/grab-gaming-consoles-at-discounted-rates-during-amazon-great-indian-festival-up-to-72-off-71760602352327.html" data-item-product-position="2" data-item-story-segment="NA" data-item-event="story_click" data-item-page-name="story page" data-item-widget-element="image"> ### sendGA4Events(this), 0)" data-item-widget-name="gaming" data-item-story-type="story" data-item-story-title="Grab gaming consoles at discounted rates during Amazon Great Indian Festival: Up to 72% off" data-item-target-url="tech.hindustantimes.com/gaming/grab-gaming-consoles-at-discounted-rates-during-amazon-great-indian-festival-up-to-72-off-71760602352327.html" data-item-product-position="2" data-item-story-segment="NA" data-item-event="story_click" data-item-page-name="story page" data-item-widget-element="title"> Grab gaming consoles at discounted rates during Amazon Great Indian Festival: Up to 72% off](https://tech.hindustantimes.com/gaming/grab-gaming-consoles-at-discounted-rates-during-amazon-great-indian-festival-up-to-72-off-71760602352327.html)
[sendGA4Events(this), 0)" data-item-widget-name="gaming" data-item-story-type="story" data-item-story-title="Pokémon GO Wild Area 2025 to bring Grimmsnarl family, Shiny Hatenna, and global challenges" data-item-target-url="tech.hindustantimes.com/gaming/news/pokmon-go-wild-area-2025-to-bring-grimmsnarl-family-shiny-hatenna-and-global-challenges-71756381158954.html" data-item-product-position="3" data-item-story-segment="news" data-item-event="story_click" data-item-page-name="story page" data-item-widget-element="image"> ### sendGA4Events(this), 0)" data-item-widget-name="gaming" data-item-story-type="story" data-item-story-title="Pokémon GO Wild Area 2025 to bring Grimmsnarl family, Shiny Hatenna, and global challenges" data-item-target-url="tech.hindustantimes.com/gaming/news/pokmon-go-wild-area-2025-to-bring-grimmsnarl-family-shiny-hatenna-and-global-challenges-71756381158954.html" data-item-product-position="3" data-item-story-segment="news" data-item-event="story_click" data-item-page-name="story page" data-item-widget-element="title"> Pokémon GO Wild Area 2025 to bring Grimmsnarl family, Shiny Hatenna, and global challenges](https://tech.hindustantimes.com/gaming/news/pokmon-go-wild-area-2025-to-bring-grimmsnarl-family-shiny-hatenna-and-global-challenges-71756381158954.html)
[sendGA4Events(this), 0)" data-item-widget-name="gaming" data-item-story-type="story" data-item-story-title="Shade Silver free on Steam for a limited time: Here’s how to get it" data-item-target-url="tech.hindustantimes.com/gaming/news/shade-silver-free-on-steam-for-a-limited-time-here-s-how-to-get-it-71755589849487.html" data-item-product-position="4" data-item-story-segment="news" data-item-event="story_click" data-item-page-name="story page" data-item-widget-element="image"> ### sendGA4Events(this), 0)" data-item-widget-name="gaming" data-item-story-type="story" data-item-story-title="Shade Silver free on Steam for a limited time: Here’s how to get it" data-item-target-url="tech.hindustantimes.com/gaming/news/shade-silver-free-on-steam-for-a-limited-time-here-s-how-to-get-it-71755589849487.html" data-item-product-position="4" data-item-story-segment="news" data-item-event="story_click" data-item-page-name="story page" data-item-widget-element="title"> Shade Silver free on Steam for a limited time: Here’s how to get it](https://tech.hindustantimes.com/gaming/news/shade-silver-free-on-steam-for-a-limited-time-here-s-how-to-get-it-71755589849487.html)
[sendGA4Events(this), 0)" data-item-widget-name="gaming" data-item-story-type="story" data-item-story-title="Call of Duty: Black Ops 7 skips Switch 2 at launch, release date and price leak" data-item-target-url="tech.hindustantimes.com/gaming/call-of-duty-black-ops-7-skips-switch-2-at-launch-release-date-and-price-leak-71755498652282.html" data-item-product-position="5" data-item-story-segment="NA" data-item-event="story_click" data-item-page-name="story page" data-item-widget-element="image"> ### sendGA4Events(this), 0)" data-item-widget-name="gaming" data-item-story-type="story" data-item-story-title="Call of Duty: Black Ops 7 skips Switch 2 at launch, release date and price leak" data-item-target-url="tech.hindustantimes.com/gaming/call-of-duty-black-ops-7-skips-switch-2-at-launch-release-date-and-price-leak-71755498652282.html" data-item-product-position="5" data-item-story-segment="NA" data-item-event="story_click" data-item-page-name="story page" data-item-widget-element="title"> Call of Duty: Black Ops 7 skips Switch 2 at launch, release date and price leak](https://tech.hindustantimes.com/gaming/call-of-duty-black-ops-7-skips-switch-2-at-launch-release-date-and-price-leak-71755498652282.html)
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